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Participants on the 12 mg dose lost an average of 28.7% of body weight (approximately 71.2 lbs) at 68 weeks

They have not been evaluated by the Food and Drug Administration, and are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety

However, the effects of GLP-1 agents and other glucose-lowering drugs on cancer risk are not well established

GLP-1 response to oral glucose is reduced in prediabetes, screen-detected type 2 diabetes, and obesity and influenced by sex: The ADDITION-PRO Study

The clinical reality is that GLP-1 receptor agonists like semaglutide and tirzepatide can influence sexual desire through multiple overlapping pathways