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Journal of Clinical Psychopharmacology 2024;44(2):8995

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Mild and Uncommon Side Effects Digestive Discomfort Some users may experience: Mild bloating or stomach discomfort, especially when taken on a completely empty stomach Slight nausea at higher doses Temporary loose stools during the first few days These effects are usually short-term and often settle within 35 days as the body adjusts

The decision ultimately comes down to balancing convenience, cost, and clinical complexity