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Cells were harvested by centrifugation and resuspended in 15 ml lysis buffer (300 mM NaCl, 10% glycerol, 50 mM TrisHCl (pH 8.1) and 10 mM MgCl 2 ) containing 6 U DNase I

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To be eligible, participants had to be between 25 and 40 years of age, to be healthy as per site physician medical assessment, to be working for 812 h per day, and to have a body mass index (BMI) between 18.5 and 27.5 kg/m 2

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