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Roy Chowdhury SK, Sangle GV, Xie X, Stelmack GL, Halayko AJ, Shen GX

In this model, ligation acts as (i) a mechanical trauma on the dentogingival area, thereby reducing tissue integrity and allowing for intense host-plaque interaction and (ii) a plaque-formation-promoting factor, thus increasing the number of bacteria

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The answer depends on three major factors: The specific peptide used The dosage and administration method Medical supervision Many peptides have been safely used in medicine for decades

The GHK-Cu half life is so remarkably short that it demands a completely different approach compared to more stable peptides