Understanding MTHFR Gene Variants First lets define what your test results show you
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Studies show that the C667T and A1298C variants increase the relative risk : high homocysteine, stroke, and heart disease[ref][ref][ref][ref][ref] neural tube defects and cleft lip[ref] preeclampsia and hypertension in pregnancy[ref][ref] miscarriage[ref][ref] depression or anxiety[ref][ref][ref][ref][ref] Alzheimers[ref][ref] autism spectrum disorder (C677T only according to 2026 meta-analysis)[ref] rare problems with nitrous oxide[ref], but most have no problems[ref] Lets dig into the details of what research studies and clinical trials show
[DOI] [PubMed] [Google Scholar] 77.Reljanovic M., Reichel G., Rett K., Lobisch M., Schuette K., Mller W., Tritschler H.J., Mehnert H
They accumulate in your tissues and organs (ovaries, thyroid, adrenal glands) and interfere with normal hormonal function