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Prolonged overdose of B6 (150-200 mg/day) over weeks can cause severe sensory-nervous-system dysfunction and ataxia.37 With normal usage serious adverse effects are not reported for pyridoxine (vitamin B6), however, diarrhoea, emesis and rosacea-like dermatitis may be observed in some cases (38)
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This phenomenon, which is known as the 'somatopause', has led to recombinant human GH being widely promoted and abused as an antiageing drug, despite lack of evidence of efficacy
J Agric Food Chem 52(3):445450 Kang WS et al (2023) Therapeutic potential of Peucedanum japonicum Thunb
S.OikonomouE.PapamikroulisG.-A.VogiatziG.PapaioannouS.et al (2019)
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