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In dogs at 52 weeks of treatment at the NOAEL of 40 mg/kg, which is approximately 3 times the MRHD (400 mg) on a mg/m2 body surface area, the AUC7d values were approximately 59 mcgh/mL in males and 44 mcgh/mL in females

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Calcium is a mineral essential for healthy bones and is also important for muscle contraction,

Systematic reviews show positive results for chronic tendinopathy (especially lateral epicondylitis and patellar tendinopathy) and knee osteoarthritis