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doi: 10.1007/s00424-003-1117-9 103 CarrELKelmanAWuGSGopaulRSenkevitchEAghvanyanAet al

Lyophilized (dry) powder is considerably more stable and should be kept frozen until reconstitution

This review does not comprehensively address APAP toxicity in specific vulnerable populations, such as neonates, pediatric patients, pregnant women, or the elderly, who may exhibit distinct pharmacokinetics, pharmacodynamics, and susceptibility to liver injury