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Also, patients should be warned about the danger of taking folic acid in place of vitamin B 12, because the former may prevent anemia but allow progression of subacute combined degeneration
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Vitamin B12 has a very low toxicity profile as it is water-soluble and excess amounts are excreted through urine
Since B12 is also essential for fetal development, particularly the development of the neural tube, low B12 can increase the risk of birth defects if left unaddressed in pregnant women
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