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By working through multiple receptor systems, the mix may prevent or overcome compensatory mechanisms that limit single-peptide effect

Diabetes Metab 101508 Schirra J, Nicolaus M, Woerle HJ, Struckmeier C, Katschinski M, Gke B (2009) GLP-1 regulates gastroduodenal motility involving cholinergic pathways

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Thyroid disorders can affect sexual function, though this connection is indirect and thyroid dysfunction would typically present with multiple other symptoms