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Supplementation to the horses with MSM was able to provoke a recovery of GPx and GR activities, presumably due to a reduction in oxidative and inflammatory damage induced by the improvement of GSH, and NO levels, as will be discussed later

Hormonal changes, such as shifts in estrogen levels due to menopause, tend to worsen swelling

doi: 10.1007/s12094-025-03987-x 5 Medetgul-ErnarKDavisMM

Additionally, we explored whether such abnormalities could also be seen in the muscle, and whether there is a relationship between changes in the brain (central origin of symptoms) and in muscle (peripheral origin of symptoms)

Hong M, Lee VM