it can promote what's called plaque stability in those arteries, making the plaque less likely to break off and close off that artery, and then it almost works like a blood thinner in lab animals in terms of reducing platelet clumping." She added, "When you combine that with weight loss, [there are] significant cardio protective effects."

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The deepest body of mechanistic work on GHK-Cu has come from Loren Pickart and collaborators, who have published extensively on its biology across more than four decades (Pickart et al., 2015) In preclinical research, GHK-Cu has been associated with effects on collagen and glycosaminoglycan synthesis in dermal fibroblast models, on hair-follicle morphology in rodent and ex-vivo skin studies, and on expression of genes involved in tissue remodeling
This makes it effective for weight loss by helping patients eat less and feel more satisfied