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However, some patients may be advised to withhold Rybelsus temporarily, particularly if they: Are experiencing significant gastrointestinal side effects Are in the dose-escalation phase of treatment Have known gastroparesis or delayed gastric emptying Are undergoing procedures with higher aspiration risk If your clinical team does recommend withholding Rybelsus, they will provide specific instructions about when to stop

You feel uncomfortably full, bloated, or pressured in your lower belly

Warfarin: This common blood thinner can interact with semaglutide, altering its effectiveness

Smriti Choudhary, MD, and Dr

Lack of Clinical Evidence: There is currently limited research supporting the safety and efficacy of combining different GLP-1 medications