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10.1016/j.cell.2011.02.013 [DOI] [PubMed] [Google Scholar] Hasan, R., Yasaei, H., Matta, S., Marriott, A., Newbold, R., & Roberts, T

While extensive trials in human subjects are lacking, studies to date in both animal and human models are highly favorable

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Inhibition of fatty acid synthase with FT-4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non-alcoholic fatty liver disease: results from two early-phase randomized trials