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This review focuses on six commonly abused drugs (Table 1), classified based on their pharmacological and neurotoxic profiles: Psychostimulants: Methamphetamine (METH), cocaine and synthetic cathinones (bath salts) primarily act on monoaminergic systems, leading to disruptions in dopamine, serotonin, and norepinephrine signaling ( 2 O predominantly affect glutamatergic transmission by antagonizing NMDA receptors (NMDARs), causing excitotoxicity, mitochondrial dysfunction, and neuronal apoptosis

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Adherence to Dosing: Take all medications exactly as prescribed

By dampening this response, semaglutide helps to keep blood sugar levels more stable and reduces the risk of dangerous blood sugar spikes and crashes

10.1210/en.2011-0253 Endocrinology 86 StorchK