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Neural involvement in CF has been proposed [66,67,68]

Narula HS, Carlson HE

The research to date shows a relatively favorable safety profile in limited human studies, but long-term safety and large-scale clinical trials are lacking

Vitamin A (primarily as retinol) coordinates HFSC fate by modulating its levels, directing stem cells toward either wound healing or hair growth (Tierney et al., 2024)

Clinically, I have seen that having the MTHFR variation doesnt necessarily mean one is destined for a lot of health challenges and symptoms, and having a greater number of variations doesnt always mean the person will have more symptoms