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The gamma-glutamyl cycle should be considered not as a mechanism for amino acid transport but rather a generator of extracellular signals, gamma-glutamyl amino acids, that are converted intracellularly to 5-oxoproline, which activates uptake and/or metabolism of amino acids (1, 74, 75)

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Ebselen, one of the efficient GPx mimics, has shown promising results with regard to radioprotection against lethal doses of -radiation in the preliminary studies [57,58,59]