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Birsoy and colleagues also found how mitochondrial glutathione drives cancer spread: not by acting as an antioxidantan effect ruled out through multiple experimentsbut by signaling to activate ATF4, a transcription factor that helps cancer cells survive in low-oxygen conditions

The next day, blots were washed three times with TBS plus Tween 20 and incubated at room temperature for 1 hr with horseradish peroxidase-conjugated secondary antibodies (1:3,000 dilution, Santa Cruz)

doi: 10.1097/00003246-200205000-00010 53 CecilianiFCeronJJEckersallPDSauerweinH

244 Martins, L