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Among the tested matrices, M05 and M09 demonstrated better retention of viable cells during the later fermentation phase, as supported by both DeltaLog (CFUs) values trends

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results showing that oral GLP-1 agonist orforglipron significantly reduced A1C at all doses and induced weight loss at 12 mg and 36 mg versus placebo, with a safety profile consistent with the GLP-1 class

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