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Reduced form (GSH)

Furosemide and rosuvastatin were given as single doses, whereas the OCs were dosed to steady state in order to provide clinically relevant exposures while taking pharmacokinetics and tolerability of the compounds into consideration

no oxidation HalfLife in Aqueous Solution: ~24 hours (oxidizes to GSSG)

Add in the nausea, vomiting or diarrhoea that many people experience in the early weeks of treatment, and your body is losing these minerals faster than it can replace them

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