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doi: 10.1093/intimm/dxw002 492 FrederiksenBLiuERomanosJSteckAYinXKroehlMet al

Mechanistic studies would be strengthened by isoform-specific NOS experiments, FAK or paxillin pathway inhibition, VEGFR2 pathway modulation, direct measurement of endothelial and fibroblast markers, and rescue experiments that test whether blocking one pathway prevents downstream effects