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Role in Detoxification GSTs function in cellular protection by catalyzing the conjugation of GSH with numerous hydrophobic and electrophilic intermediates, including many carcinogens, therapeutic agents, and products of oxidative stress, rendering them less toxic and facilitating their export from the cell

Why this timing

10.1002/ajmg.b.30366 27 JamesS

At present, Spectroscopy (a type of MRI scan) can provide utility in some situations, but ongoing studies of brain structure and chemicals reflect the late pathophysiology of FA and thus are unlikely to be early markers of disease or early effects of treatment

In addition, glucagon receptor stimulation increases energy expenditure, enhances fat oxidation, and improves lipid metabolism, contributing significantly to adipose tissue reduction (Elkasrawy & Hamrick, 2024)