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Through molecular interaction experiments (such as Co-IP and dual-luciferase reporter gene assays), the regulatory mechanisms between p53 and key target molecules such as SLC7A11 and FOXO3 can be analyzed to elucidate the molecular switch of its bidirectional effects

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Microcytic anemia (low MCV, typically below 80 fL) most commonly indicates iron deficiency, thalassemia, or anemia of chronic disease

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